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Who Might Have a Genetic Cancer Predisposition?
The characteristics of genetic cancer families include an early age at diagnosis, bilateral tumors and multiple generations affected along the same family line.
Indications for a Cancer Genetics Evaluation include:
Breast and Ovarian Cancer
- You or 2 close relatives had breast cancer diagnosed at age 50 or younger.
- You or a close relative had bilateral breast cancer, first diagnosed at age 50 or younger.
- You and 2 close relatives had ovarian cancer and/or breast cancer.
- Any male who has had breast cancer or a close relative of a male who has had breast cancer.
- You are Ashenazi Jewish diagnosed with breast cancer when you were younger than age 50 OR have had ovarian cancer at any age.
- You have a close relative with an identified BRCA1 or BRCA2 mutation.
Colorectal Cancer
- You had colon or uterine cancer diagnosed at age 45 or younger.
- You had 2 colon cancer or colon AND uterine cancer at any age.
- You have 2 close relatives with colon cancer; one diagnosed at 55 years old or younger.
- You have 3 close relatives with colorectal and/or uterine cancer at any age.
- You or a close relative have been clinically diagnosed with polyposis.
Other Cancer Syndromes
- You or your close relatives have a history of multiple primary tumors (particularly endocrine, bone or brain) at early ages.
- You have many relatives with cancers diagnosed at early ages (<50 years).
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